C. O. Bigelow Apothecaries is an American pharmacy and beauty brand currently owned and operated by Ian Ginsberg. C. O. Bigelow was founded, as The Village Apothecary Shop, by Dr. Galen Hunter in 1838 in New York's Greenwich Village and is the oldest surviving apothecary–pharmacy in the United States.In the late 1800's, the pharmacy was purchased by Clarence Otis Bigelow, who renamed the store after himself. He subsequently built the Bigelow Building at 414 Sixth Avenue, and in 1902 the pharmacy moved into the new location where it has remained ever since. During the Great Depression, the store had become run-down, and it was sold to William B. Ginsberg, an Eastern-European immigrant who came to New York and earned his Doctorate of Pharmacy from Columbia University. The Ginsberg family has owned and operated the apothecary since 1939, passing from William, to his son Jerry Ginsberg, and eventually to his son Ian Ginsberg. Alec Ginsberg, Ian's son and fourth generation pharmacist, currently serves as the company's Chief Operating Officer after joining full-time in 2016.
Limited Brands had an agreement to open and operate other stores bearing the Bigelow name, which were operated as upscale beauty and skin care stores to compete with other stores such as Sephora and Neiman Marcus. However, all of these stores were closed, leaving only the original shop. Certain products from the line are sold in Bath and Body Works stores throughout the United States, as well as many other retail stores worldwide.
Due to its longevity and popularity, C. O. Bigelow was honored with a Village Award from the Greenwich Village Society for Historic Preservation in 2002.

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